CAS 1414-45-5
Is Nisin preparation banned where you sell?
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Banned, limited, needs a warning, or no rule we know of. US states also follow federal rules, shown in their own row.
For Packaged food and beverages: Conformity: Must meet the conditions of Nisin preparation (21 CFR 184.1538) may be used in food only as the section provides: the specifications, the foods and the limits written in § 184.1538.. In force since 6 Apr 1988.
The section's conditions of use (foods, limits, specifications, labelling) are written in § 184.1538 and are not broken down here. Section text as written: "(b) The ingredient is a concentrate or dry material that meets the specifications that follow when it is tested as described in “Specifications for Identity and Purity of Some Antibiotics,” World Health Organization, FAO Nutrition Meeting Report Series, No. 45A, 1969, which is incorporated by reference. Copies are available from the Dockets Management Staff (HFA-305), Food and Drug Administration, 5630 Fishers Lane, Rm. 1061, Rockville, MD 20852, 240-402-7500, between 9 a.m. and 4 p.m., Monday through Friday, or available for inspection at the National Archives and Records Administration".
“§ 184.1538 Nisin preparation. (a) Nisin preparation is derived from pure culture fermentations of certain strains of Streptococcus lactis Lancefield Group N. Nisin preparation contains nisin (CAS Reg. No. 1414-45-5), a group of related peptides with antibiotic activity.”
We have no rule for it here. Our coverage starts 1 Jan 2025, and this doesn't mean it's allowed.
We have no rule for it here. Our coverage starts 19 Aug 2026, and this doesn't mean it's allowed.
We have no rule for it here. Our coverage starts 13 Nov 2025, and this doesn't mean it's allowed.
We have no rule for it here. Our coverage starts 1 Apr 2026, and this doesn't mean it's allowed.
We have no rule for it here. Our coverage starts 8 Oct 2026, and this doesn't mean it's allowed.
- Status
- Other requirement
- Requirement, dates and source
For Packaged food and beverages: Conformity: Must meet the conditions of Nisin preparation (21 CFR 184.1538) may be used in food only as the section provides: the specifications, the foods and the limits written in § 184.1538.. In force since 6 Apr 1988.
The section's conditions of use (foods, limits, specifications, labelling) are written in § 184.1538 and are not broken down here. Section text as written: "(b) The ingredient is a concentrate or dry material that meets the specifications that follow when it is tested as described in “Specifications for Identity and Purity of Some Antibiotics,” World Health Organization, FAO Nutrition Meeting Report Series, No. 45A, 1969, which is incorporated by reference. Copies are available from the Dockets Management Staff (HFA-305), Food and Drug Administration, 5630 Fishers Lane, Rm. 1061, Rockville, MD 20852, 240-402-7500, between 9 a.m. and 4 p.m., Monday through Friday, or available for inspection at the National Archives and Records Administration".
“§ 184.1538 Nisin preparation. (a) Nisin preparation is derived from pure culture fermentations of certain strains of Streptococcus lactis Lancefield Group N. Nisin preparation contains nisin (CAS Reg. No. 1414-45-5), a group of related peptides with antibiotic activity.”
Parts 172-189 substance sections, 21 CFR 184.1538, Subpart Listing of Specific Substances Affirmed as GRAS · fetched 2026-10-09US National Archives / Office of the Federal Register (eCFR): 21 CFR Part 184 (eCFR, version of 2026-10-07)(opens in a new tab)
- Status
- No known rule
- Requirement, dates and source
We have no rule for it here. Our coverage starts 1 Jan 2025, and this doesn't mean it's allowed.
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- Not covered
- Requirement, dates and source
We hold no rules for this market.
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- Not covered
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We hold no rules for this market.
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- Not covered
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We hold no rules for this market.
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- Not covered
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We hold no rules for this market.
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- Not covered
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We hold no rules for this market.
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- Not covered
- Requirement, dates and source
We hold no rules for this market.
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- Not covered
- Requirement, dates and source
We hold no rules for this market.
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- Not covered
- Requirement, dates and source
We hold no rules for this market.
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- Not covered
- Requirement, dates and source
We hold no rules for this market.
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- Not covered
- Requirement, dates and source
We hold no rules for this market.
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- Not covered
- Requirement, dates and source
We hold no rules for this market.
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- Not covered
- Requirement, dates and source
We hold no rules for this market.
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- Not covered
- Requirement, dates and source
We hold no rules for this market.
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- Not covered
- Requirement, dates and source
We hold no rules for this market.
- Status
- Not covered
- Requirement, dates and source
We hold no rules for this market.
- Status
- No known rule
- Requirement, dates and source
We have no rule for it here. Our coverage starts 19 Aug 2026, and this doesn't mean it's allowed.
- Status
- No known rule
- Requirement, dates and source
We have no rule for it here. Our coverage starts 13 Nov 2025, and this doesn't mean it's allowed.
- Status
- No known rule
- Requirement, dates and source
We have no rule for it here. Our coverage starts 1 Apr 2026, and this doesn't mean it's allowed.
- Status
- No known rule
- Requirement, dates and source
We have no rule for it here. Our coverage starts 8 Oct 2026, and this doesn't mean it's allowed.
California
Prop 65 listing
California's list of chemicals known to cause cancer or reproductive harm.
Not on the Prop 65 list in our data
Not on California's list when we last checked it.
Groups
Group memberships
Groups that name this substance. Markets define groups like PFAS in different ways.
Not named in any group
No group we track names this substance. Groups like PFAS are defined by chemical structure and don't list members, so whether it's in one depends on your product.
Records
Recalls and alerts
Recalls, safety alerts and Prop 65 notices that name Nisin preparation, with a link to the original. A Prop 65 notice is a claim by the sender, not a ruling.
No records in our feeds
No Prop 65 notice, EU Safety Gate alert or CPSC recall has named Nisin preparation since January 2023. Other agencies may still have acted.
See also
Related
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