CAS 50-18-0
Is Cyclophosphamide (anhydrous) banned where you sell?
4 markets have rules for it. Selling something that contains it? Check it free, no account needed.
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Status
Status by market
Banned, limited, needs a warning, or no rule we know of. US states also follow federal rules, shown in their own row.
We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: 1 Jan 2025; Packaged food and beverages: 7 Oct 2026; Consumer electronics and small appliances: 1 Jan 2025; Batteries, e-bikes and power banks: 1 Oct 2026), and this doesn't mean it's allowed.
Warning required when exposure exceeds the threshold (NSRL (µg/day): 1). In force since 27 Feb 1988.
- Chemical
- Cyclophosphamide (anhydrous)
- Type of toxicity
- cancer
- Listed by
- the Labor Code (LC)
- CAS No.
- 50-18-0
- Date listed
- 27 Feb 1987
- NSRL or MADL (µg/day)
- 1
Prop 65 list row: Cyclophosphamide (anhydrous) · fetched 2026-10-08
California OEHHA: 27 CCR 27001(opens in a new tab)Warning required when exposure exceeds the threshold (no MADL listed for this row). In force since 1 Jan 1990.
- Chemical
- Cyclophosphamide (anhydrous) developmental, female, male SQE - developmental FR -
- Type of toxicity
- female reproductive toxicity, male reproductive toxicity
- CAS No.
- 50-18-0
- Date listed
- 1 Jan 1989
Prop 65 list row: Cyclophosphamide (anhydrous) · fetched 2026-10-08
California OEHHA: 27 CCR 27001(opens in a new tab)We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: 1 Jan 2025), and this doesn't mean it's allowed.
We have no rule for it here. Our coverage starts 1 Jan 2025, and this doesn't mean it's allowed.
We have no rule for it here. Our coverage starts 1 Jan 2025, and this doesn't mean it's allowed.
We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: 1 Jan 2025), and this doesn't mean it's allowed.
We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: 1 Jan 2025), and this doesn't mean it's allowed.
We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: 1 Jan 2025), and this doesn't mean it's allowed.
We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: 1 Jan 2025), and this doesn't mean it's allowed.
We have no rule for it here. Our coverage starts 1 Jan 2025, and this doesn't mean it's allowed.
We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: 1 Jan 2025), and this doesn't mean it's allowed.
We have no rule for it here. Our coverage starts 1 Jan 2025, and this doesn't mean it's allowed.
We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: 1 Jan 2025; Batteries, e-bikes and power banks: 16 Sep 2023), and this doesn't mean it's allowed.
We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: not covered; Consumer electronics and small appliances: 1 Jan 2025), and this doesn't mean it's allowed.
We have no rule for it here. Our coverage starts 1 Jan 2025, and this doesn't mean it's allowed.
We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: 1 Jan 2025), and this doesn't mean it's allowed.
We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: 1 Jan 2025), and this doesn't mean it's allowed.
For Cosmetics and personal care: Banned. In force since 11 Jul 2013.
From the consolidated text: Cyclophosphamide (INN) and its salts · 50-18-0 · 200-015-4
Annex II entry 88 · fetched 2026-10-09
European Commission / Publications Office (CELLAR): Reg. (EC) 1223/2009 Annexes II-VI(opens in a new tab)For Cosmetics and personal care: Banned. In force, start date unknown.
From the official list: Cyclophosphamide (INN) and its salts · 50-18-0 · 200-015-4
Annex II entry 88 · fetched 2026-10-10
The National Archives (legislation.gov.uk): Reg. (EC) 1223/2009 (retained) Annexes II-VI(opens in a new tab)We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: 12 Jul 2024; Packaged food and beverages: 1 Apr 2026; Consumer electronics and small appliances: 3 Sep 2026; Batteries, e-bikes and power banks: 1 Sep 2026), and this doesn't mean it's allowed.
For Cosmetics and personal care: Banned. In force under the consolidated notice effective 18 Mar 2026; earlier versions are not in our data.
From the official list: 시클로포스파미드 및 그 염류 · 50-18-0 · 시클로포스파미드
Schedule 1 시클로포스파미드 및 그 염류 · fetched 2026-10-09
Ministry of Food and Drug Safety / National Law Information Center (law.go.kr): 화장품 안전기준 등에 관한 규정 별표 1, 별표 2, 제6조(opens in a new tab)- Status
- No known rule
- Requirement, dates and source
We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: 1 Jan 2025; Packaged food and beverages: 7 Oct 2026; Consumer electronics and small appliances: 1 Jan 2025; Batteries, e-bikes and power banks: 1 Oct 2026), and this doesn't mean it's allowed.
- Status
- Warning required
- Requirement, dates and source
Warning required when exposure exceeds the threshold (NSRL (µg/day): 1). In force since 27 Feb 1988.
- Chemical
- Cyclophosphamide (anhydrous)
- Type of toxicity
- cancer
- Listed by
- the Labor Code (LC)
- CAS No.
- 50-18-0
- Date listed
- 27 Feb 1987
- NSRL or MADL (µg/day)
- 1
Prop 65 list row: Cyclophosphamide (anhydrous) · fetched 2026-10-08
California OEHHA: 27 CCR 27001(opens in a new tab)Warning required when exposure exceeds the threshold (no MADL listed for this row). In force since 1 Jan 1990.
- Chemical
- Cyclophosphamide (anhydrous) developmental, female, male SQE - developmental FR -
- Type of toxicity
- female reproductive toxicity, male reproductive toxicity
- CAS No.
- 50-18-0
- Date listed
- 1 Jan 1989
Prop 65 list row: Cyclophosphamide (anhydrous) · fetched 2026-10-08
California OEHHA: 27 CCR 27001(opens in a new tab)
- Status
- No known rule
- Requirement, dates and source
We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: 1 Jan 2025), and this doesn't mean it's allowed.
- Status
- No known rule
- Requirement, dates and source
We have no rule for it here. Our coverage starts 1 Jan 2025, and this doesn't mean it's allowed.
- Status
- No known rule
- Requirement, dates and source
We have no rule for it here. Our coverage starts 1 Jan 2025, and this doesn't mean it's allowed.
- Status
- No known rule
- Requirement, dates and source
We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: 1 Jan 2025), and this doesn't mean it's allowed.
- Status
- No known rule
- Requirement, dates and source
We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: 1 Jan 2025), and this doesn't mean it's allowed.
- Status
- No known rule
- Requirement, dates and source
We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: 1 Jan 2025), and this doesn't mean it's allowed.
- Status
- No known rule
- Requirement, dates and source
We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: 1 Jan 2025), and this doesn't mean it's allowed.
- Status
- No known rule
- Requirement, dates and source
We have no rule for it here. Our coverage starts 1 Jan 2025, and this doesn't mean it's allowed.
- Status
- No known rule
- Requirement, dates and source
We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: 1 Jan 2025), and this doesn't mean it's allowed.
- Status
- No known rule
- Requirement, dates and source
We have no rule for it here. Our coverage starts 1 Jan 2025, and this doesn't mean it's allowed.
- Status
- No known rule
- Requirement, dates and source
We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: 1 Jan 2025; Batteries, e-bikes and power banks: 16 Sep 2023), and this doesn't mean it's allowed.
- Status
- No known rule
- Requirement, dates and source
We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: not covered; Consumer electronics and small appliances: 1 Jan 2025), and this doesn't mean it's allowed.
- Status
- No known rule
- Requirement, dates and source
We have no rule for it here. Our coverage starts 1 Jan 2025, and this doesn't mean it's allowed.
- Status
- No known rule
- Requirement, dates and source
We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: 1 Jan 2025), and this doesn't mean it's allowed.
- Status
- No known rule
- Requirement, dates and source
We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: 1 Jan 2025), and this doesn't mean it's allowed.
- Status
- Banned
- Requirement, dates and source
For Cosmetics and personal care: Banned. In force since 11 Jul 2013.
From the consolidated text: Cyclophosphamide (INN) and its salts · 50-18-0 · 200-015-4
Annex II entry 88 · fetched 2026-10-09
European Commission / Publications Office (CELLAR): Reg. (EC) 1223/2009 Annexes II-VI(opens in a new tab)
- Status
- Banned
- Requirement, dates and source
For Cosmetics and personal care: Banned. In force, start date unknown.
From the official list: Cyclophosphamide (INN) and its salts · 50-18-0 · 200-015-4
Annex II entry 88 · fetched 2026-10-10
The National Archives (legislation.gov.uk): Reg. (EC) 1223/2009 (retained) Annexes II-VI(opens in a new tab)
- Status
- No known rule
- Requirement, dates and source
We have no rule for it here. Our coverage starts 1 Jan 2025 (Home and kitchen goods: 1 Jan 2025; Cosmetics and personal care: 12 Jul 2024; Packaged food and beverages: 1 Apr 2026; Consumer electronics and small appliances: 3 Sep 2026; Batteries, e-bikes and power banks: 1 Sep 2026), and this doesn't mean it's allowed.
- Status
- Banned
- Requirement, dates and source
For Cosmetics and personal care: Banned. In force under the consolidated notice effective 18 Mar 2026; earlier versions are not in our data.
From the official list: 시클로포스파미드 및 그 염류 · 50-18-0 · 시클로포스파미드
Schedule 1 시클로포스파미드 및 그 염류 · fetched 2026-10-09
Ministry of Food and Drug Safety / National Law Information Center (law.go.kr): 화장품 안전기준 등에 관한 규정 별표 1, 별표 2, 제6조(opens in a new tab)
California
Prop 65 listing
California's list of chemicals known to cause cancer or reproductive harm.
- Listing
- Listed 1987-02-27 (cancer). Grace period: "Proposition 65 warning requirements do not apply until 12 months after the chemical has been listed" (Appendix A); listing date plus 12 months.
- Warning applies from
- 27 Feb 1988
- Requirement
- Warning required when exposure exceeds the threshold (NSRL (µg/day): 1)
- Warning wording
- This product can expose you to Cyclophosphamide (anhydrous), which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
- Chemical
- Cyclophosphamide (anhydrous)
- Type of toxicity
- cancer
- Listed by
- the Labor Code (LC)
- CAS No.
- 50-18-0
- Date listed
- 27 Feb 1987
- NSRL or MADL (µg/day)
- 1
Prop 65 list row: Cyclophosphamide (anhydrous) · fetched 2026-10-08
California OEHHA: 27 CCR 27001(opens in a new tab)- Listing
- Listed 1989-01-01 (developmental, female, male). Grace period: "Proposition 65 warning requirements do not apply until 12 months after the chemical has been listed" (Appendix A); listing date plus 12 months.
- Warning applies from
- 1 Jan 1990
- Requirement
- Warning required when exposure exceeds the threshold (no MADL listed for this row)
- Warning wording
- This product can expose you to Cyclophosphamide (anhydrous), which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
- Chemical
- Cyclophosphamide (anhydrous) developmental, female, male SQE - developmental FR -
- Type of toxicity
- female reproductive toxicity, male reproductive toxicity
- CAS No.
- 50-18-0
- Date listed
- 1 Jan 1989
Prop 65 list row: Cyclophosphamide (anhydrous) · fetched 2026-10-08
California OEHHA: 27 CCR 27001(opens in a new tab)Groups
Group memberships
Groups that name this substance. Markets define groups like PFAS in different ways.
Not named in any group
No group we track names this substance. Groups like PFAS are defined by chemical structure and don't list members, so whether it's in one depends on your product.
Records
Recalls and alerts
Recalls, safety alerts and Prop 65 notices that name Cyclophosphamide (anhydrous), with a link to the original. A Prop 65 notice is a claim by the sender, not a ruling.
No records in our feeds
No Prop 65 notice, EU Safety Gate alert or CPSC recall has named Cyclophosphamide (anhydrous) since January 2023. Other agencies may still have acted.
See also
Related
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Every rule for this kind of product, in each market.
- Consumer electronics and small appliances
Every rule for this kind of product, in each market.
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